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DIAMINE OXIDASE 9001-53-0
Category : Organic chemicals and Derivatives
CAS NO : EC NO : 232-613-6 MF : MW : Specification : ≥90.0% Packing : packed in aliminum foil bag and carton box or plastic bag and carton drum Product description : DIAMINE OXIDASE Chemical Properties storage temp. ?20°C solubility 100 mM sodium phosphate buffer, pH 7.2: soluble10mg/mL Safety Information Safety Statements 22-24/25 WGK Germany 3 DIAMINE OXIDASE Usage And Synthesis Definition An enzyme occurring in the animal digestive system; it converts histidine to histamine. Biological Functions Diamine oxidase attacks both diamines and histamine in much the same way that MAO attacks monoamines, forming aldehydes. This enzyme is inhibited by carbonyl-blocking reagents and produces hydrogen peroxide, supporting the role of pyridoxal phosphate and the flavin prosthetic groups in the catalytic action of the enzyme. Diamine oxidase is recovered in the supernatant after centrifugation and removal of particulate matter. It is present in kidneys, intestines, liver, lung, and nervous tissue. It limits the biological effects of histamine and the polymethylene amines putrescine and cadaverine. It also attacks monoamines, but at a higher substrate concentration.Plasma amine oxidases are in blood plasma of mammals and include spermine oxidase, which deaminates spermine and other polyamines. Uses : organic chemicals Synonyms : amine oxidase, copper-containing;diamine oxidase;
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